16 trials, more than 6,400 postmenopausal women.
Pooling randomized trials, researchers found vitamin K2 improved bone mineral density at the lower spine, especially when combined with vitamin D or calcium. No significant change was seen at the hip.
- Who
- 6,425 postmenopausal women
- Daily dose
- MK-7, 45–375 mcg (or MK-4)
- Design
- Meta-analysis of 16 RCTs